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Unicyte submits Clinical Trial Application for potentially life-saving therapy for pediatric patients with urea cycle disorders, setting the stage for patient enrollment in H2 2022 Unicyte AG, a clinical-stage development company innovating the field of regenerative medicine, today announced the submission of a Clinical Trial Application (CTA) in Europe for a Phase 2 trial (reLiver-2) designed to assess the safety and efficacy of its proprietary human liver stem cell (HLSC) therapy, HLSC-001, in pediatric patients with early-onset urea cycle disorders (UCD). HLSC-001 is being evaluated in these patients initially as a bridging therapy prior to liver transplantation with the option and ultimate goal to provide a curative therapy. The company expects to initiate patient enrollment in the second half of
Published at Front Cell Dev Biol.
©2021
by Bruno S, Herrera Sanches MB, Chiabotto G, Fonsato V, Navarro-Tableros V, Pasquino C, Tapparo M, Camussi G.
Published at Transplantation Int.
©2021
by De Stefano N, Navarro-Tableros V, Roggio D, Calleri A, Rigo F, David E, Gambella A, Bassino D, Amoroso A, Patrono D, Camussi G, Romagnoli R.
Published at J Mol Sci
®2020
by Brossa A, Fonsato V, Grange C, Tritta S, Tapparo M, Calvetti R, Cedrino M, Fallo S, Gontero P, Camussi G, Bussolati B.
Published at Sci Rep
©2020
by Famulari ES, Navarro-Tableros V, Herrera Sanchez MB, Bortolussi G, Gai M, Conti L, Silengo L, Tolosano E, Tetta C, Muro AF, Camussi G, Fagoonee S, Altruda F.
Published at Stem Cell Rev Rep.
®2020
by Spada M, Porta F, Righi D, Gazzera C, Tandoi F, Ferrero I, Fagioli F, Sanchez MBH, Calvo PL, Biamino E, Bruno S, Gunetti M, Contursi C, Lauritano C, Conio A, Amoroso A, Salizzoni M, Silengo L, Camussi G, Romagnoli R.
Published at Hindawi, Stem Cells Int.
©2019
by Stefania Bruno, Maria Beatriz Herrera Sanchez, Chiara Pasquino, Marta Tapparo, Massimo Cedrino, Ciro Tetta, Giovanni Camussi
Published at Stem Cells
2018
by Navarro-Tableros V. Gai, C, Gomez Y, Giunti, S, Pasquino C, Deregibus M, Tapparo M, Pitino A, Tetta C, Brizzi M, Ricordi C, Camussi G.
Published at Cell Transplant.
®2012
by Cantaluppi V, Biancone L, Figliolini F, Beltramo S, Medica D, Deregibus MC, Galimi F, Romagnoli R, Salizzoni M, Tetta C, Segoloni GP, Camussi G.